Category Archives: Telomeres Telomerase

Isagenix Video Exclusive Brain and Sleep Renewal System

Over 50% of people in the US over age 50 report some problems with memory and thinking.
This percentage only increases over time.


More alarming is new research reporting the onset of memory loss for people in their 20′s and 30′s.
Our brain, is easily argued is our most vital organ. Anyone who is intent on leading the highest quality life needs to have a strategy for looking after our brain both day and night.

IsaGenix Brain Support
There is something you can do now to insure healthy brain aging. Introducing the IsaGenix Brain and Sleep Renewal Support System.

Brain Boost and Renewal is a proprietary blend of natural ingredients scientifically formulated and clinically tested to support healthy brain function and increased cognitive function.

When taken daily Brain Boost and Renewal helps improve mental clarity, focus, concentration and memory.

Considering that the majority of brain renewal and body repair happens during sleep, getting not just good but high quality sleep is a goal we should all take seriously.

Poor sleep quality is associated with health problems like binge eating, cognitive decline, impaired memory and shorter telomeres.

Sleep Support and Renewal is an all-natural fast acting melatonin spray that contains vital nighttime nutrients for the brain and body to really feel the benefits of great sleep quality like improved focus, memory and alertness.

Sleep Support and Renewal is best taken with Brain Boost and Renewal for the best results take these two products daily.

You can take the complete IsaGenix Cleansing system that includes IsaLean Shakes and Ageless Essentials Daily Pak with Product B.

Proper nutrition, rest and lifestyle habits are essential for healthy brain aging.

With the IsaGenix Brain and Sleep Renewal System you’ll enjoy a healthy brain and revitalizing sleep for years to come.

Isagenix Product B Available in Australia, New Zealand, Hong Kong, Canada, Puerto Rico

Product B (IsaGenesis) is available in the US, however it is also available in the following countries Australia, New Zealand, Hong Kong, Canada, Puerto Rico with more countries on the way..

Now New Improved -Contains increased actions, a greater bioavailability of ingredients and 30 percent higher ORAC value, this product is now more effective than ever!


This fourth generation of Isagenix Product B is so improved, it comes with a new name—Product B IsaGenesis®—and it’s scientifically designed to deliver the optimal levels of active ingredients targeted to support telomere health.

Product B IsaGenesis aims to help telomeres do what they do best—protect your DNA, your cells and help you age healthily.

“Besides being the best telomere support product on the planet,” said John Anderson, “IsaGenesis is also a very powerful antioxidant, which benefits the liver and the brain.”

Outstanding New Improvements

  • 20 percent more active ingredients
  • Ingredients added to enhance absorption
  • It’s now a softgel, making it easier to swallow
  • Also supports liver, kidney and brain health, cell integrity and healthy circulation

“Oxidative stress, toxins and a poor diet can cause the process of telomere shortening to speed up, which means we age faster in life. And the faster we age, the sooner we face age-related health conditions down the road.”

More Information on Product B IsaGenesis including Ordering – Click Here!

International Ordering of IsaGenix Product B IsaGenesis– Click Here!

After clicking the link above then select the Products Tab And Then “Healthy Aging Solutions” and then Product B IsaGenesis. Or call us at 1-877-824-7692 -trust me it’s easier. Or email us at sjslifep @ mindspring.com

Article How Oxidative Stress Shortens Telomeres

Here is an excellent article on how free radicals – oxidative stress can impact and even shorten telomeres. This is not a good thing.

Can you imagine entering the doctor’s office one day and obtaining a blood test that measures your biological age, as a better indicator of health than chronological age? That day could arrive soon with tests that measure the length of telomeres.

Images of Embryonic and Adult Stem Cells, DNA, and Telomeres
Embryonic and Adult Stem Cells, DNA, and Telomeres

Substantial evidence has led to findings that premature aging and its core cellular mechanisms are governed by the onset of telomere shortening (1-5). In this article, we hope to help increase understanding of the relationship between chronic oxidative stress and telomere instability.

The glutathione (GSH)-dependent antioxidant system is the cell’s primary defense against oxidative stress, and plays a major role in detoxification and bolstering the body’s immune system. Emerging data are helping to explain the role of the GSH-redox cycle for preserving telomeres.

Structurally, telomeres are formed by non-coding DNA sequences along with specialized proteins that act as protective caps at the physical ends of chromosomes. Human telomeric DNA consists of repeated sequences of TTAGG and extends over several thousand base pairs. Because guanine-rich sequences are more sensitive and less capable of DNA repair, telomeres are more vulnerable to oxidation.

Telomeres fold back onto themselves in a loop to provide functional stability. The telomeric DNA is synthesized by the enzyme telomerase, the absence of which results in a progressive erosion. Evidence indicates that chronic oxidative stress not only causes progressive damage to cellular membranes, proteins, and molecules, but also induces the slowing down of existing telomerase activity and accelerates telomere shortening (1&2).

Chronic oxidative stress develops into a state of progressive telomere shortening induced by elevated homocysteine levels, and reduced glutathione, or an otherwise compromised GSH-redox cycle.

Lower amounts of reduced glutathione, and diminished activity of the enzymes GSH peroxidase and catalase, cause a failure to protect cell components from damaging peroxides (1-3). The mitochondria become dysfunctional, producing increasing amounts of free radicals and less ATP energy (1-3). Together, these effects lead the cell to cease division or appropriate function, known as replicative senescence.

Guarding the GSH-antioxidant System

Because the GSH-antioxidant system is the predominant guardian against oxidative stress, it is proposed that maintaining its integrity can support against telomere erosion and “stress-induced” premature onset of accelerated aging.

Scientific research suggests that a variety of consistent behaviors in humans in-vivo are available to alter the amount of oxidative stress placed on cells of the body.

Among factors thought to adversely affect telomeres are smoking, drinking heavily, obesity, and chronic psychological stress (1-3). On the other hand, meditation, socialization, and regular exercise are associated with longer telomeres (1-3).

In addition, studies suggest diet and supplementation habits can be help preserve telomere integrity. Some choices linked with longer telomeres are:

  • consuming higher amounts of omega-3 fatty acids
  • obtaining higher amounts of vitamin D, maintaining a healthy weight, eating a diet higher in dietary fiber (particularly insoluble fiber)
  • drinking green tea regularly
  • and taking a quality multivitamin (containing sufficient amounts of B vitamins, vitamins A, C, and E) daily (4)

Whey to Glutathione

Another method to gain optimal  protection against oxidative stress and telomere attrition is by using methods to naturally increase the levels of glutathione in the body by way of regular ingestion of whey protein, according to recent studies (5-7).

Bioactive whey protein,” as one study calls it, provides a high concentration of the amino acids cysteine, glutamate, and glycine. These amino acid precursors are used in the synthesis of glutathione by the enzyme GSH-synthase. Several studies have shown that bioactive whey protein can dramatically raise the levels of glutathione in the cells of the body without side effects (5 & 6). Increases in levels of circulating glutathione from whey are associated with a stronger immune system and greater capacity of detoxification.

Whey also offers other anti-aging benefits such as protection against sarcopenia (the loss of muscle and strength with age) and by supporting weight management through increases of thermogenesis and satiety.

Supplementing to Optimize Telomere Protection

Supplementing with antioxidant vitamins and minerals supports activity of antioxidant enzymes that can assist in protecting cells and their components, including telomeres, against oxidative stress.

GSH peroxidase plays a major role using GSH as its reducing agent in detoxification of peroxides (types of reactive oxygen species, such as hydrogen peroxide), which can inflict harm to cell membranes, proteins, and telomeric DNA.

The oxidized GSH is then recycled by another enzyme, GSH reductase, which uses nicotinamide adenine dinucleotide phosphate (NADPH) as its coenzyme and reducing agent. Catalase is also an enzyme that acts as an efficient detoxifier of hydrogen peroxide, while superoxide dismutases (SOD) are a class of enzymes that act to quench superoxide, a highly reactive form of oxygen, and convert it to hydrogen peroxide or stabilized oxygen.

It’s notable that selenium, niacin, zinc, and copper are important dietary factors because these enzymes rely on them to function.

Interestingly, data are emerging that particular dietary factors and supplements could act to promote antioxidant enzyme activity further and thereby further support telomere integrity. These supplements will be subject of future blog posts.

Isagenix IsaGenesis Product – Click Here!

More Information Product B including Ordering – Click Here!

Isagenix Announces New University Clinical Study Findings on Product B

Here are the results of a new clinical study conducted at Arizona State University evaluating Product B and its  impact on aging in the body.
Telomeres image and Product B
First here is some basic information on telomeres- they are a marker of aging.

The length of telomeres, or the caps on the ends of chromosomes that protect DNA in cells, is the key to healthy aging. In the simplest terms, “when telomeres get short, bad things happen.” To live a long and healthy life, scientists have offered guidelines for telomere health that include controlling stress, getting optimal nutrition, obtaining quality sleep, minimizing toxin exposure, and finally, bolstering antioxidant defenses against free radicals and reactive oxygen species.

“As we age, our cells are constantly dividing and our telomeres shorten during the process,” explains molecular biologist and telomere researcher Bill Andrews, Ph.D. “Oxidative stress, toxins, and a poor diet can cause the process of telomere shortening to speed up, which means we age faster in life. And the faster we age, the sooner we face age-related health conditions down the road.”

That’s where Product B™ comes into the picture. As part of its Healthy Aging Solution, Isagenix features Product B as a proprietary formula of potent bioactives, botanicals, and vitamins with antioxidants to support the health of telomeres. Extensive and detailed research accompanied the creation of Product B  followed by an Isagenix commitment to continued research and development of the product through collaboration with industry experts and leading experts.

Now Isagenix has announced results of a new clinical study at Arizona State University evaluating Product B impact on aging in the body involving a key biomarker that is associated with antioxidant defenses in cells. The findings were presented at the company’s 2014 “Strength in Momentum” Celebration in San Diego on August 24, 2014.

“There have been large advances in telomere science, including direct measurements related to detecting cells with the shortest telomeres or average telomere length using sophisticated techniques,” said Isagenix Chief Science Officer Suk Cho, Ph.D. However, he added that to date, “There is yet to be a direct measure of telomeres that is reliable enough for an accurate measurement of telomere length for obtaining statistical significance in a clinical trial.”

But there’s good news. As Dr. Cho explained, “Leading telomere researchers agree that direct telomere testing is not where we’d like it. However, there is an indirect measurement that is supported in the scientific literature that is linked to telomere health.”

The indirect measurement involves the antioxidant enzyme, catalase. Catalase is one of the body’s major antioxidant enzymes that is associated with increased longevity in experimental models of aging (1,2). The antioxidant enzyme’s main responsibility is to prevent the toxic accumulation of hydrogen peroxide. Hydrogen peroxide is a free radical that is widely found in the body, but that can also be found in the diet. Catalase has an essential role that the body relies on to protect against hydrogen peroxide’s long-known harm to telomeres and DNA.

Study Details

Recently, Isagenix funded an independent, randomized, placebo-controlled, double-blind clinical trial–the “gold standard” in research–to evaluate the effects of Product B on the antioxidant defense systems that are essential for maintaining healthy telomeres and warding off signs of premature cellular aging. The study, conducted by researchers in the School of Nutrition and Health Promotion at Arizona State University, involved 43 young healthy men and women. The researchers divided the subjects into two groups supplemented with either four capsules per day of a placebo or Product B.

At the end of the study, the subjects using Product B showed a significant elevation of catalase in subjects’ red blood cells. Compared to those who took the placebo, the subjects on Product B had increased their catalase activity by more than 30 percent. The findings suggest profound benefits attributed to Product B supplementation.

The relevance of this finding was not lost on the researchers, who commented, “The increase in catalase observed by Product B is an exciting development considering the relationship between the enzyme and increased lifespan in animal studies.”

 Other IsaGenesis Product B Ingredients Info – Click Here!

IsaGenesis – New Generation of IsaGenix Product B is Now Available

The subject line says it all.  Isagenix Co-Founder and President Jim Coover and Master Formulator John Anderson have just revealed a new formulation of Product B®!


This fourth generation of Product B is so improved, it comes with a new name—Product B IsaGenesis®—and it’s scientifically designed to deliver the optimal levels of active ingredients targeted to support telomere health.

“Isagenix cares about telomere health and we are committed to be in the forefront of this science using natural products, not drugs,” said Jim Coover during the reveal. Product B IsaGenesis aims to help telomeres do what they do best—protect your DNA, your cells and help you age healthily.

“Besides being the best telomere support product on the planet,” said John Anderson, “IsaGenesis is also a very powerful antioxidant, which benefits the liver and the brain.”

Outstanding New Improvements

  • 20 percent more active ingredients
  • Ingredients added to enhance absorption
  • It’s now a softgel, making it easier to swallow
  • Also supports liver, kidney and brain health, cell integrity and healthy circulation

The new formulation boasts another improvement: It’s now a softgel, making it easier to swallow and superior in terms of absorption of the active ingredients. “All Isagenix products are formulated with these fundamental objectives in mind,” said John Anderson also shared the origin of the product’s new name, saying, “I always knew the name would change someday as the product evolved.

Genesis means the coming into being of something, it means the origin. And that is exactly what IsaGenesis is as Isagenix leads the way to telomere health—now and in the future.” Dr. Bill Andrews, a pioneer in the world of telomere health, was also present for the reveal, where he shared some basics of telomere science and new advances in research. “As we age, our cells are constantly dividing and our telomeres shorten during the process,” Dr. Andrews explains.

“Oxidative stress, toxins and a poor diet can cause the process of telomere shortening to speed up, which means we age faster in life. And the faster we age, the sooner we face age-related health conditions down the road.”

To Order IsaGenesis – Click Here!

Then select the Products Tab And Then “Healthy Aging Solutions” and then Product B IsaGenesis. Or call us at 1-877-824-7692 -trust me it’s easier.

 

 

 

Grape Seed Extract OPC Nutrition for Telomeres Anti-Aging Support

The following video details many of the benefits of grape seed extract – OPC – one of the many ingredients in Product B Telomeres Anti-Aging Supplement.
Grapes for grape seed extract

Check out the following video.

Video on YouTube – Click Here!

Grape seed extract is a very potent antioxidant. One of the main health providing ingredients in it is OPC. OPC’s were pioneered by Dr Jacques Masquelier in the late 1940′s after WWII. Resveratrol is another very valuable polyphenol contained in grape seed extract.

Many believe grape seed extract – OPC is why we have what is called the French Paradox in that people in France who drink a lot of red wine don’t tend to have a lot of heart problems. Even though they smoke and eat a lot of fatty foods.

More on IsaGenix Product B for Telemeres – Click Here!

Dr Bill Andrews Appears on NBC Today Show Discusses Telomeres and Telomerase.

Dr. Bill Andrews , was guest on an episode of the NBC Today Show. This particular show discussed aging research and how scientists were looking for solutions that could extend human lifespans up to 150 years old. The following video was taken from the show.

Watch Dr Bill Andrews NBC Today Show Telomeres video on YouTube – Click Here!

Dr Bill Andrews on Today Show

Dr. Andrews likes to say “Bad things happen when telomeres get short.” This Today Show segment detailed how Dr. Bill Andrews is working on finding a solution for extending human life, in effect overcoming aging. His research has focused on keeping telomeres from becoming short.

Order Information and More on Telomeres and Product B – Click Here!

IsaGenix Product B Telomeres Ingredients Video – Click Here!

Product B Telomeres Support by Isagenix is nominated for the World’s first supplement of the year award

Product B Telomeres Support by Isagenix is nominated for the World’s first supplement of the year award.
Alive Conference Product B Telomeres Support IsaGenix
ALIVE New York 2012 is the World’s biggest celebrity health event and awards show taking place June 21st & 22nd, 2012.

This is the first time where such an announcement has been made in the health & wellness industry. The new anti-aging science regarding Telomeres, won the the Noble Prize in Medicine, has made Isagenix’s new Product B, the most advanced supplement known to mankind in this day and age. With the telomere science quickly evolving, it is no surprise that this is the year that the world has decided to vote on a “The World’s Supplement of the Year Award”.

Isagenix has more patents than any company worldwide in the telomere research and development field. Product B is leading the way in anti-aging telomere science.

ALIVE New York will be global live streaming in over 50 countries with speakers such as David Wolfe, Dr. Robert Young author of “The pH Miracle”, Brendan Brazier, Founder of Vega, and more. It is estimated that the audience of ALIVE New York will potentially surpass 30 million viewers through the live stream.

There is also talk that the Isagenix formulators of Product B, Dr. John Anderson and DNA Telomere Research Dr.Bill Andrews will also be there to explain at this pay per view event the telomere roll behind aging and why it is having such a huge impact recently in the anti-aging & wellness industries.

With this science, the researches have found a way to stop and reverse the aging process in rats so far. Since it’s release in April of 2011, Product B by Isagenix consumers are making bold statements regarding how more vibrant and healthy they feel just after a month’s of use. Reports of amazing energy and mental clarity have also been noticed almost instantly. Research on the results is currently underway.
Today Show with Dr. Bill Andrews Telomeres and Telomerase Anti-Aging Support – Click Here!

Also Check out the IsaGenix Product B Antioxidants Plus Telomere Support Product – Click Here!

Also – Telomeres Dr. Bill Andrews and IsaGenix Product B – Click Here!

Today Show with Dr. Bill Andrews Telomeres and Telomerase Anti-Aging Support

Dr. Bill Andrews , was featured on the December 13th episode of the NBC Today Show. It was part of a segment that discussed how scientists were researching aging and looking for solutions that could extend human lifespans up to 150 years old. The following video was taken from the show.

The video-show discussed how Dr. Bill Andrews is working on finding a solution for extending human life, in effect overcoming aging. His research has focused on keeping telomeres from becoming short. As Dr. Andrews has said “Bad things happen when telomeres get short.”

IsaGenix Product B – Telomeres Support Product. (Co-Developed by Dr. Bill Andrews.)

Label of Product B Antioxidants and Telomere Support Ingredients and More Info – Click Here!

Telomeres Science Facts and IsaGenix Product B

The Science of Telomeres is really very simple :

1. Telomeres are our ‘Body Clock’. They shorten with normal cell division.

  • They are caps of repetitive DNA at the ends of our chromosomes.
  • They shorten as the cells in our bodies divide.
  • 15,000 units long when we are conceived,
  • 10,000 units long when we are born,
  • Our telomeres continue to shorten with each cell division throughout our life, and when they get down to 5,000, WE DIE!

2. Telomerase is an enzyme that causes Telomeres to lengthen.

3. A Gene to produce Telomerase is present in every cell in our bodies.

4. Bad things happen when telomeres get short.

5. ‘Product B’ is a nutraceutical that contains substances that have been proven to support telomeres.

Here are some basic facts about IsaGenix Product B
IsaGenix Product B Telomeres bottle
It is a proprietary, scientifically advanced formula of antioxidants for protecting telomeres and stimulating more efficient antioxidant enzyme-defense systems.

As part of your body’s normal aging process, each time a cell divides the telomeres in your DNA get shorter. Add oxidative stress, obesity, poor nutrition, and toxicity to the mix and telomeres shorten even more rapidly.

Antioxidants fight free radicals and stem the causes of oxidative stress, but a key combination of antioxidants is needed to reduce the effects of oxidative stress on your telomeres.

Certain natural ingredients in Product B have been shown to induce telomerase in-vitro. In-vitro lab results may not be indicative of in-vivo results.

Here are some recent comments – what people are saying about Product B

”I have unbelievable energy!”

“I’m running around with toddlers and have energy to spare!”

“I have never felt better!”

“I began taking Product B in September 2010. The changes are both visible and invisible, but the biggest change is that I’ve lost all semblance of my age. If it weren’t for my driver’s license, I’d feel like I was 25. I have more energy, and every day I feel more and more alive. I went skiing recently and didn’t feel sore afterward.”
– Peter G

“My energy went through the roof. I recently went on a trip to Europe, and I didn’t feel sluggish with the time change.
Susan S.

“I’ve always been energetic, but with Product B I’m running faster and further. I’m so fired up about this product!”
Kathy C

Be sure to watch the Video of Bill Andrews on Telomeres, Product B and Aging – Click Here!

Another great telomeres resource is the following: This webpage analyzes the various botanicals contained in IsaGenix Product B – Click Here!

Here as an example is the writeup on Resveratrol Extract Nutrition Information – Click Here!